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diabetic gastroparesis, may be linked to upper gastrointestinal symptoms for which current treatment remains suboptimal

Carmot Therapeutics has revealed preliminary data from the single ascending dose (SAD) portion of its ongoing Phase 1 clinical trial for CT-996, an oral small molecule GLP-1 receptor agonist (RA) currently being evaluated in a first-in-human clinical trial in participants with obesity or overweight.CT-996 is a once-daily oral, small molecule GLP-1 receptor agonist being developed for the treatment of obesity and type 2 diabetes (T2D)

However, no direct link has been found between GLP-1R agonists and higher pulmonary aspiration risk

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2026, Perez, Sarah

This review provides an objective assessment of their program, examining its effectiveness, safety, cost, and accessibility