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All in Group 3 received an ICD

However, as the saying goes, "with great power comes great responsibility" specifically to your digestive system and muscle mass

Meanwhile, Holland & Barrett continues to invest in its own-brand weight management ranges with new launches planned throughout 2026 and beyond

Metabolic factors influencing menstrual function during weight loss: Leptin levels: This adipocyte-derived hormone decreases with fat loss and plays a crucial role in reproductive function signaling Insulin sensitivity: Improved insulin sensitivity can normalize androgen levels, particularly beneficial in PCOS Inflammatory markers: Reduction in chronic low-grade inflammation associated with obesity Sex hormone-binding globulin (SHBG): Levels typically increase with weight loss, affecting free hormone availability For women with obesity-related reproductive dysfunction, particularly those with PCOS, moderate and sustained weight loss often improves menstrual regularity over time