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The exact schedule depends on your starting health, your other medications, and how you tolerate the drug

Curr Pharm Des 29(41):32633265 Makri ES, Makri E, Polyzos SA (2022) Combination therapies for nonalcoholic fatty liver disease

When a Doctor Might Consider Both There are rare circumstances where a medical professional might suggest using both, though this is usually done off-label. Overcoming a Plateau: If a patient has seen great success on semaglutide but has stopped losing weight despite consistent effort, a doctor might temporarily add a low dose of orlistat to see if it helps restart progress

But then Eli Lilly launched Zepbound, its weight-loss drug, as sales of its diabetes-focused GLP-1, Mounjaro, also rose

Hes really starting to come out of his shell now, Dawn said

But dont overlook hydration, either