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31% of GLP-1 users drank less alcohol in the past year

Two major ongoing trials are likely to change that, with potentially big implications for clinical practice.

GLP-1 receptor agonists improve MASH mostly via extrahepatic actions: 1 CNS appetite control weight loss systemic inflammation 2 Chylomicron synthesis & improve lipid metabolism 3 Bind gut immune cells anti-inflammatory + microbiome benefits 4 Reduce adipose & pancreatic inflammation
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