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Ultimately, the EPOs Board of Appeal (BoA) rejected this evidence as basis for establishing an unexpected technical effect of the claimed subject matter and emphasised that commercial success could not retroactively establish inventive step if the claimed features were already suggested by the prior art at the priority date
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Given the high immunogenicity associated with the full-length CHIPS protein, CHOPS was designed as a minimized analogue that retains the essential receptor-binding residues identified from structural studies of CHIPS in complex with C5aR
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Rama Al-Shiab, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey
