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Clinical trial data from the STEP 1 and SURMOUNT-1 trials show that patients typically achieve 1015% total body weight loss with semaglutide 2.4 mg weekly (Wegovy) and 1520% with tirzepatide 1015 mg weekly (Zepbound) over 1218 months

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Document how you feel after each injection in a simple notes app, tracking nausea, appetite suppression, and energy levels to identify patterns

When excess weight or visceral adiposity is not a major driver of symptoms, menopause treatment focuses on hormone or non-hormonal symptom management rather than weight-loss medication

Fabi reports being a speaker, investigator, and consultant for AbbVie, Galderma, Merz Therapeutics, Revelle Aesthetics, and Endo Aesthetics

Some people with diabetes can go their entire lifetime without complications