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Available from: le Roux CW, Steen O, Lucas KJ, Startseva E, Unseld A, Hennige AM

In summary, tirzepatide represents a significant conceptual and therapeutic shift in the treatment of type 2 diabetes and obesity

It peaks around weeks two through four and typically resolves by week eight to twelve

However, more meaningful and measurable weight loss typically becomes evident after about four to eight weeks of consistent use

The FDA says state-licensed compounding pharmacies must immediately stop making most compound versions of GLP-1 drugs based on tirzepatide

It works by enhancing insulin secretion, reducing glucagon levels, slowing digestion, and regulating appetite