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Clinical trials showed average weight loss of 5-8% of body weight with liraglutide 3.0mg daily, roughly half of what semaglutide or tirzepatide achieves

Comparing Semaglutide to Other GLP-1 Weight Loss Medications Semaglutide and tirzepatide (a GLP-1/GIP dual receptor agonist) both produce significant weight loss, but tirzepatide generally delivers 3-5% greater total body weight reduction in head-to-head trials

Mandatory screening must confirm no history of Pancreatitis or Medullary Thyroid Carcinoma (MTC)

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