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For additional product-specific information on agents from the GLP-1 RA class, please refer to the companion lesson titled: An Overview of GLP-1 RAs: What Every Pharmacist Should Know. PUTTING IT ALL TOGETHER: CASE REVIEW AND DISCUSSION Case scenario JM is a 65-year-old man with T2D of 8 years duration

conducted the literature search

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells

doi: 10.1089/chi.2025.0007

Each lawsuit contains substantially similar allegations about GLP-1 RAs and their alleged propensity to cause gastrointestinal injuries

Directly activating PKA and EPAC raises cAMP quickly