converting between glp-1 agonists GLP-1-based therapies for type 2 diabetes: from single, dual and triple to endogenous production and L-cell differentiation | Diabetology & Metabolic Syndrome Switching Between Glucagon-Like Peptide-1 Receptor
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The fat bomb exploded but no one heard the bang

10.1093/jnci/djae260 112 WibergS.KjaergaardJ.SchmidtH.ThomsenJ

Its anti-inflammatory mechanisms operate entirely through GLP-1R activation

An interesting question is whether one of these hormones contributes more to tirzepatides effects than the other

If slow titration does not work to minimize side effects, suggest small food portions and make sure any reflux symptoms are appropriately treated (a short course of a proton pump inhibitor is most commonly recommended) (Gorgojo-Martnez JJ et al, J Clin Med 2022;12(1):145)

SCALE Obesity and Prediabetes NN8022-1839 Study Group
