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doi: 10.1016/j.diabet.2025.101641

2024;7(8):e2427258

Liraglutide injection into the VMH of mice induced weight loss and increased thermogenetic activity, as evidenced by elevated uncoupling protein 1 expression in both BAT and white adipose tissue, with adenosine monophosphate-activated protein kinase (AMPK) signaling in the VMH required as a mediator [71]

Wang et al., 2024), and then improves the blood glucose level

Our therapies restore energy, support fat loss, and reduce risk for future disease

More concerning still, the prevalence of severe obesity, defined as a BMI 35 kg/m 2 with at least one comorbidity or a BMI 40, was 9.7% [6]
