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Retatrutide's triple-agonist approach produced even greater weight loss, with Phase 3 TRIUMPH-4 confirming 28.7% at 68 weeks

Metabolic adaptation

I would not be surprised if SUD eventually became a clinical indication for using a GLP-1. Lacking that, DeRoo said that the ideal patients who can benefit from GLP-1 off-label uses across mental health are those who already meet clinical criteria to receive a prescription for a GLP-1

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Dosage level: Tirzepatide doses range from 2.5 mg to 15 mg