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Not getting the appropriate amount of sleep, which is 7 to 8 hours a night, is associated with greater visceral fat mass, says Sherrie Khadanga, MD, a cardiologist and assistant professor of medicine at the University of Vermont Medical Center in South Burlington

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Tirzepatide-Specific Considerations Tirzepatide appears to have slightly higher rates of GI side effects compared to Semaglutide in head-to-head trials, though discontinuation rates remain relatively low

As such, postprandial secretion of GIP, GLP-1, and GLP-2 inhibits bone resorption and/or promotes bone formation, representing a gut-bone axis