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In summary, the STEP studies were important to confirm the efficacy of SMG in weight loss in individuals with obesity or overweight associated with comorbidities (Table 4), leading to the approval of the indication of SMG 2.4 mg (Wegovy ) for weight loss in this subpopulation

Those with a history of pancreatitis need careful evaluation before starting

Checking multiple sources helps find better rates

Many patients report experiencing less food obsession, which can free them to focus on other meaningful parts of life

Endogenous GLP-1 has a short plasma half-life of about 2-3 min (46)

Uncontrolled diabetes can lead to complications during or after a donation