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Cutting your dose to save money or avoid side effects can reduce effectiveness increase rebound risk and may expose you to contaminated or inaccurate products

Both target the GLP-1 receptor, but tirzepatide also targets the insulinotropic polypeptide (GIP) receptor, making it a GIP/GLP-1 receptor agonist

PMID: 37931265

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For patients with weight related health conditions such as high blood pressure or obesity, this difference can be clinically significant

While small molecules like nicotine or estrogen can be absorbed via a patch, GLP-1 molecules are roughly ten times larger than the limit for skin absorption