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doi: 10.1161/CIRCULATIONAHA.118.036418

Regulatory authorities continue to review emerging safety data as longer-term studies become available, ensuring that prescribing guidance reflects the most current evidence base

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Additional indications Knee osteoarthritis, sleep apnea, MASLD, cardiovascular outcomes, and chronic low back pain would follow based on their respective trial timelines This mirrors how Lilly handled tirzepatide: Mounjaro was approved for diabetes first (May 2022), followed by Zepbound for obesity (November 2023)

Blood Glucose Effects: For patients with type 2 diabetes taking both medications, Wegovy's glucose-lowering effects should be considered, particularly if other antidiabetic medications are prescribed