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Description
The dose-response relationship is well established
doi: 10.1016/j.neuron.2015.09.016 192 SatterstromF
After reaching a plateau around week 40 to 44, participants maintained their weight through week 48 with minimal regain of only 0.8kg on average
10.1530/jme-15-0293 57
Its once-weekly dosing, broad physician preference, and extensive real-world evidence drive sustained adoption
Lilly has also confirmed that orforglipron is being studied for weight-related conditions such as obstructive sleep apnea (OSA) and high blood pressure (hypertension) in adults with a BMI of 27 or higher
