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Side effects included nausea (44%), vomiting (24%), diarrhea (30%), constipation (24%), abdominal pain (20%), headache (14%), fatigue (11%), dizziness (8%), abdominal distension (7%), and belching (7%)

Estradiol modulates the anorexic response to central glucagon-like peptide 1

Cycling GLP-1 RA treatment induces therapeutic resistance and rebound obesity