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The GLP-1 RA monitoring report describes more detailed information about the overall population of patients being prescribed these medications (including demographics, comorbidities, social drivers of health data like income and education, and more), and the proportion and characteristics of patients who actually filled a GLP-1 RA prescription over time using dispenses

Given the strength of these preliminary signals, the field must now shift focus toward conducting well-powered phase 3 RCTs to validate these associations

Initially approved for the treatment of Type 2 diabetes, its benefits have extended beyond just controlling blood glucose levels and obesity treatment

Since the late 1990s, several pharmacological agents have received regulatory approval for chronic weight management in both Europe and the United States

Therefore, this review aims to summarize the key medicinal plants with reported antidiabetic activity, their major bioactive molecules, and the mechanisms through which they contribute to the management of diabetes mellitus

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