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The development of reliable non-invasive biomarkers is essential for reducing the dependency on liver biopsies and improving the accuracy of clinical trials
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A pooled analysis of tirzepatide, currently the only GIP/GLP-1 receptor agonist, in 4036 participants regardless of diabetes status, for a treatment duration of 12 to 72 weeks, showed a significant weight loss of mean difference of 7.7 kg (8.1%), 11.6 kg (11.9%), and 11.8 kg (12.4%) compared to placebo for doses of 5, 10, and 15 mg, respectively
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