tirzepatide use in pregnancy of GLP-1 drugs early should not cause alarm, analysis suggests Can the new diabetes and
Description
No clinical trial has tested this combination, and it is not recommended
13 Significant secondary endpoints included weight reduction of at least 20%
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The tablet should be taken on an empty stomach with up to 120 mL of plain water, at least 30 minutes before food, drink or other oral medicines
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Compared with placebo, semaglutide 2.0 mg (risk ratio = 7.73 [95% CI 5.62, 10.63]) and tirzepatide 15 mg (risk ratio = 7.01 [95% CI 5.73, 8.57]) were the most efficacious in achieving an HbA 1c target of 48 mmol/mol (6.5%) (ESM Table 9)
