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doi: 10.1007/S12020-021-02945-1 57 KatoleNTSalankarHVKhadeAMKaleJSBankarNJGosaviPet al

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Recently, a working group from the International Consortium for Health Outcomes Measurement (ICHOM) made recommendations for a standard set of practical and validated psychosocial measures [179], including the WHO-5 Wellbeing Index (WHO-5) [180], Problem Areas in Diabetes (PAID) scale [181], and Patient Health Questionnaire (PHQ-9) [182]

In addition to impaired EEC signaling and gut peptide release, GF models have impaired ENS activation compared with conventionalized and specific-pathogen-free models 245,246

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