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Steady-state exposure typically occurs after 4 to 5 weeks of weekly administration, and disrupting that rhythm slows things down

The abdomen is most commonly used

Yet, the concentration of digoxin remained within its therapeutic range with no need for dosage adjustment

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Meanwhile, Novo Nordisk is another major player in the GLP-1 space, having invested heavily in Ozempic and Wegovy (both semaglutide) with a recent $4.1 billion investment in its manufacturing space in Clayton, North Carolina.