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Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes (Sutton et al.) Cell Metabolism (Cell Press) 2018 Landmark RCT supporting the claim that time-restricted eating may improve insulin sensitivity and blood sugar 'particularly when the eating window sits earlier in the day,' independent of weight loss

IL-33 appears to have important roles in resolution of inflammation and tissue repair, but is also associated with both pro-inflammatory and anti-inflammatory functions in colitis mouse models

Preventative nutritional strategies, including riboflavin and CoQ10, to enhance mitochondrial efficiency

Patients awaiting UnitedHealthcare decisions face decision timelines of 5-14 business days minimum, whereas PlexusDx processes orders within 24-48 hours

Second, in humans with loss-of-function variants in SLC22A1, which decrease the uptake of metformin into the liver, the ability of metformin to lower A1c levels is not impaired (48)