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Peripherally released GLP-1 and its stable analogs (eg, exendin-4 or liraglutide) administered peripherally can access the CNS by crossing the bloodbrain barrier (BBB) directly (27) or by interacting with the circumventricular organs

The remaining patients were diagnosed with bilateral papillitis , involving swelling of both optic nerve heads, and paracentral acute middle maculopathy, affecting blood flow in part of the retina

Antidiabetic agents as a novel treatment for Alzheimer's and Parkinson's disease

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It underscores the need for more frequent monitoring when starting tirzepatide, a point we will return to in the monitoring section

The findings, published in JCI Insight external link, may inform research to support the development of tailored COVID-19 therapies." "Neutrophils or white blood cells respond to foreign immune threats, including the virus that causes COVID-19, in many ways, including a process of casting spider web-like nets, called neutrophil extracellular traps (NETs), to trap pathogens and coordinate processes to clear out potentially dangerous debris (NETosis)