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Description
Methods Blood was drawn from 24 subjects (14 male, 10 female, age: 50.77.36years, BMI: 26.643.38kg/m2, GHbA1c: 7.000.74%) with drug-nave T2D at 0 and 120min following a standard mixed meal for the measurements of active GLP-1, NO and NOS

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However, exercise shouldnt be done close to bedtime
The exendin-4-induced suppression was mimicked by perfusion with 8-Br-cAMP (a cAMP analog), but was eliminated by the protein kinase A (PKA) inhibitor Rp-cAMP/KT-5720

Plasma renin concentration remained unchanged

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