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It is estimated that nearly 60% of depressive episodes are preceded by an exposure to various types of stressors [69]

Muscle cramps are not listed as a common side effect in FDA labeling for GLP-1 receptor agonists, and clinical trials have not shown significantly higher rates compared to placebo

In this way, GLP-1 RAs exert cardiovascular and renal protective effects, improving nonalcoholic fatty liver disease through mechanisms including weight loss, blood glucose control, blood pressure reduction, lipid improvement, insulin resistance improvement, and inflammation and oxidative stress reduction [8]

[DOI] [PubMed] [Google Scholar] 186.Tibaduiza E.C., Chen C., Beinborn M

American Society of Anesthesiologists+1 In late 20242025 , multi-specialty guidance and larger studies began to suggest that most patients can safely continue GLP-1 medications , especially if they are stable on a long-term dose

[DOI] [PubMed] [Google Scholar] 41.Rosso C., Kazankov K., Younes R., et al