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Part of the GLP-1RA (Liraglutide, Semiglutide) has been verified to be efficacious in the treatment of fatty liver and is employed in the management of T2DM complicated with nonalcoholic fatty liver disease, primarily by ameliorating metabolic dysfunction, insulin resistance, and lipotoxicity of the organs related to its pathogenesis (61), decelerating the fibrosis process and reducing the liver fat content

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The Wegovy pill was also launched in the US as of early 2026, which is an oral version of the injection

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When total weight loss is 21%, even 26% of that coming from lean mass represents meaningful absolute numbers

2.4 Exposure definition The primary exposure was GLP-1 RA use, defined as any documented prescription fill for a GLP-1 RA (liraglutide, semaglutide, exenatide, and dulaglutide) at least 90 days prior to the index date, based on prescription records in the electronic health record