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It starts low and increases gradually over time under supervision, both to manage side effects and to find the dose that works for you
APOE 2 and APOE 3 mediate rapid A clearance by interacting with LRP-1, whereas APOE 4 has a higher affinity to very low-density lipoprotein receptor (VLDR) resulting in slower clearance of A and increased accumulation in the brain (van Assema et al., 2011)
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Proper preparation is key to having a positive experience on injection day
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