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Biomedicines 2023

Br J Pharmacol 173: 34433453, 2016

It is typically prescribed alongside diet and exercise to improve overall blood sugar control

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For the beneficiary to qualify, a provider must submit a prior authorization request to the program that attests the beneficiary is prescribed the requested drug to reduce excess body weight and maintain weight reduction in combination with current and ongoing lifestyle modification including structured nutrition and physical activity consistent with the applicable FDA approved label, and the beneficiary is at least 18 years of age with a BMI greater than or equal to 35. For beneficiaries with underlying medical conditions, the BMI threshold is lowered to 30 or 25 based on the diagnosis

However, these drugs are challenged with long-term effectiveness, as most patients taking Semaglutide regain two-thirds of their lost weight after one year of withdrawal (Wilding et al