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Delays stomach emptying so food stays in your system longer

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Canadian insurance can cover it Canada is not a viable market for D2C GLP-1 expansion

Martinez de Andino: GLP-1 medications slow the rate at which food leaves the stomach, so GLP-1 users stay full longer and do not feel as hungry

GLP-1 GIP NASH Trial NEJM 2024 View on PubMed 2023 Diabetes Care Mechanism Glucagon Co-Agonism Amplifies GLP-1-Mediated Weight Loss via Brown Adipose Thermogenesis Finding: In mouse models, adding glucagon receptor agonism to GLP-1R agonism increased brown adipose tissue thermogenic gene expression (UCP1 +62%, PGC-1 +44%) and significantly amplified fat oxidation (+38%)

Phase 2 trial data showed mean body weight reductions of approximately 24% over 48 weeks at the highest dose in adults with obesity without type 2 diabetes