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How GLP-1 Drugs Calm Inflammation GLP-1 drugs work through several mechanisms: Reducing oxidative stress lowering cell damage from free radicals

The critical insight is that fat loss is often still occurring during a plateau

Cellular mechanisms governing glucose-dependent insulinotropic polypeptide secretion

doi: 10.1038/ni.1993 48 HarbourSNMaynardCLZindlCLSchoebTRWeaverCT

Studies consistently show that weight regain begins soon after stopping medication and is proportional to the amount of weight originally lost: Semaglutide (Wegovy) : In the STEP 1 extension study, participants who lost an average of 17% of their body weight regained approximately two-thirds of that weight within one year of stopping the medication

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