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Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up

Many obesity specialists compare the condition to high blood pressure: Medication can help control it, but it doesn't eliminate the underlying biology

muciniphila , induce GLP-1 secretion and improve glucose homeostasis in C57BL/6J mice fed a high-fat diet (HFD) through interaction with intercellular adhesion molecule 2 (Icam-2), which activates GPCR-like downstream signals

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Shaw et al., 2005