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This leads to less fat being absorbed and more energy being burned, which may explain part of GLP-1s effectiveness in supporting weight management (Singh et al, 2024)

Secondary and sensitivity analyses In our secondary analyses, we did not observe evidence of effect measure modification by individual drug, age, sex, body mass index, history of suicidal ideation, history of depression, or socioeconomic status, as indicated by overlapping 95% confidence intervals in all comparisons (supplementary tables S4-S7)

GIP activation enhances fat metabolism and provides additional appetite suppression through the brains hunger control centers, while GLP-1 activity delivers satiety signals, with clinical studies showing up to 57% hunger reduction by week 4

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Of course, its completely normal to have some stubborn extra pounds after you give birth: The American College of Obstetricians and Gynecologists (ACOG) recommends women and pregnant people within a normal weight range gain between 25 and 35 pounds to allow for healthy fetal development