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Decisions here should be individualized and involve the prescribing clinician

Cost-effectiveness evaluation: Given the relatively recent development and potential higher cost of GLP-1 RAs and SGLT2is compared to traditional treatments, such as metformin, evaluating the cost-effectiveness of various treatment options is crucial for prioritizing in healthcare settings

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Glucagon-like peptide-1 (GLP-1)-based therapeutics: current status and future opportunities beyond type 2 diabetes

Tarumi Y, Wilson MP, Szafran O, Spooner GR

Those options havent changed in decades, and compliance rates are low
