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Results from the OUTSTAND-1 trial showed Hengrui/Kailera's HRS-7535 (KAI-7535) cut HbA1c by a highest placebo-adjusted 1.62% at 32 weeks, based on the treatment efficacy estimand.

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The incretin hormone glucagon-like peptide 1 (GLP-1) has been implicated in the gutrenal axis and incretin-based therapies might reduce the burden of diabetic kidney disease

GLP-1 weight-loss drugs pose hidden risks for young women Women taking popular weight-loss medications during their reproductive years may be unaware of associated risks to pregnancy and unborn babies, warn Flinders University researchers

GLP-1 receptor agonists have shown cardiovascular benefits beyond weight loss, including potential improvements in cholesterol profiles

For users this could segway into an expansion of the private market and for payers this could provide an affordable entry point for public reimbursement