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Amyloid and tau may be better understood as smoke, not fire, signals of metabolic stress instead of its original cause

Tirzepatide produced greater A1c reductions in the SURPASS-2 head-to-head trial, making it the stronger option for glucose control

At lower doses, appetite suppression may be minimal

In the STEP 1 and STEP 3 trials, participants with a mean BMI of 38 showed around 15% weight loss after 68 weeks treatment with 2.4mg semaglutide

Some have added BNPL options, but availability changes frequently as these partnerships evolve

Patients experiencing severe or persistent side effects should contact their provider immediately