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In contrast, GLP-1 was upregulated in IBD patients serum, when compared with controls (Keller et al

2020;130 doi: 10.1016/j.biopha.2020.110523

Tirzepatide, a dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor agonist, exhibits favourable effects on pancreatic -cells and hepatic steatosis in obese type 2 diabetic db/db mice

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The iAUC for tirzepatide was calculated from minutes 4280, using the value at minute 42 as the baseline for each sample, and is expressed as a function of time (ng/(islet min) min)
