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Search strategy and study selection We conducted a comprehensive systematic search across five electronic databases: PubMed, Embase, Web of Science, Scopus, and the Cochrane Library, as well as the Google Scholar search engine, from inception to September 30, 2025, to identify studies investigating the association between GLP-1 receptor agonists and AUD outcomes

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Whilst there is no confirmed causal link between retatrutide and depression, certain individuals may be more vulnerable to mood changes during any significant pharmacological intervention, particularly one that produces rapid and substantial weight loss

The revisited role of interleukin-1 alpha and beta in autoimmune and inflammatory disorders and in comorbidities

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