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The real danger comes from dehydration when side effects stop you drinking

This is conferred by a targeted amino acid substitution at the 8th position, replacing alanine with glutamic acid, a modification also found in exenatide-based GLP-1 therapies

While this mechanism is intentional, it can become pathological in some patients

Meanwhile, oral prescription GLP-1 options are advancing rapidly

Some insurance companies list GLP-1 medications used for weight loss as a coverage exclusion, which means that even if a patient meets FDA-approved criteria and would benefit from using the medication, the plan will not pay for the medication, she says

Ozempic is approved to treat type 2 diabetes but may be prescribed off-label for weight loss