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A high level of GIP and GLP-1 binding causes increased insulin secretion, leading to stronger control over glucose in the body [6]

This means that GLP-1 stimulates insulin release only when blood glucose levels are elevated, which significantly reduces (though does not eliminate) the risk of hypoglycaemia

2024;386: q1645

Patients using Mounjaro at higher doses have reported losing 15% to 25% of their starting body weight over 72 weeks

AT-04 is a peptibody that combines Attralus pan-amyloid removal (PAR) technology with the crystallizable fragment (Fc) portion of an IgG1 antibody