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The ESSENCE trial will provide valuable data on the maintenance of histological benefits over 240 weeks of continuous treatment, but long-term extension studies and off-treatment follow-up protocols are needed to characterize rebound kinetics

One theory behind conditions like depression and anxiety is that the brain produces too little serotonin, or absorbs it too fast, leaving too little available to help regulate moods

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You will begin the standard tirzepatide titration at 2.5 mg regardless of your previous phentermine dose