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Because oral bioavailability is lower and more variable than injectable formulations, administration timing and adherence to label instructions are clinically important

BMI is, however, a screening tool

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D., Clemmensen C., Finan B., Dimarchi R

Interestingly, less than 1% chose bariatric surgery

In addition, trials on human and mice showed GLP-1 receptor agonists benefits in heart failure, endothelial lining and,myocardial ischemia.First, heart failure clinical trials on human showed at New York Heart Association involved diabetic patients with stage 3-4 heart failure better response with Glp-1 continuous infusion over 12 weeks duration in the form of better left ventricular ejection fraction and 6 minute walk over 48 hours trial of GLP-1 infusion in nondiabetic patients with stage 2-3 heart failure