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Description
It is a pharmacological consequence of pharmacokinetics

And this might explain why so many users are noticing unexpected changes in how they experience scent

doi: 10.1111/dom.15019

Weeks 512: Acceleration of Weight Loss and Appetite Control The 512 week window is when most people experience accelerated weight loss, typically 12 pounds per week or more

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Sweeting A, Hannah W, Backman H, Catalano P, Feghali M, Herman WH