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At the time of the 2025 Super Bowl, there was a shortage of the branded GLP-1 drugs semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound, which opened the door for compounding pharmacies to sell non-identical versions under specific FDA regulations

However, those claims are not currently backed by scientific evidence or research

According to an exclusive interview with the TODAY show on Thursday, Williams has already started to see her health improve since starting the medication

These realities show that while GLP-1s help reduce weight, they rarely address the underlying metabolic factors that drive long-term weight gain

The combination of GLP-1, GIP and/or GCG agonist actions with amylinthrough the incorporation of cagrisemaglutide or amicretinopens the door to the development of new multiagonists as treatments for obesity, type 2 diabetes, and possibly other chronic diseases

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