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If you are considering supplements alongside GLP-1 therapy, discuss this with your healthcare provider first

Radiolabeled receptor binding assays show oxyntomodulin binds to the GLP-1R with an approximate 10-fold reduction in potency relative to native GLP-1, with a comparative 100-fold reduction in cAMP potency, indicating the extent of oxyntomodulins 8 amino acid C-terminal extension in conferring additional promiscuity at the GLP-1R [41]

Greasy, fried, heavily spiced, and very sweet foods are common triggers for GLP-1 related nausea

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DURATION5: exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes

doi: 10.1016/J.BRAINRES.2015.09.035 26 ShahMVellaA
