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Earlier use of pharmacotherapy is encouraged Medications should be considered early, especially in patients withor at high risk ofobesity-related complications

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While GLP-1s have dominated the conversation, amylin analogues are getting traction

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Why it Matters

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Learn how these two unlicensed medicines work, potential interactions, safety risks, and why UK specialist guidance is essential before combining them.

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GLP-1 in addiction medicine: GLP-1 acts on pancreas, gut, kidney, heart and thyroid receptors to activate reward/stress hubs (VTA, NAc, ARC, PFC, hypothalamus)

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