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A rare glimpse into the brain activity of a patient with obesity and loss of control eating on tirzepatide, marketed as Mounjaro and Zepbound, revealed that the medication suppresses signaling in the brains reward center thought to be involved in food noise but only temporarily.
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Many patients experience a weight loss plateau on semaglutide after 6-12 months
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Short-term semaglutide use can produce meaningful weight loss when combined with lifestyle changes, though research suggests sustained treatment yields better long-term results
