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GIPR is upregulated in a subset of people with bilateral macronodular adrenal hyperplasia and food-induced Cushings syndrome [166]
We recommend following the specific guidelines for your research protocol, but a 4-6 week timeframe is a common benchmark
The integrity of your research depends on this holistic approach
The STEP 1 trial showed 14.9% weight loss at 2.4 mg/week over 68 weeks (Wilding et al., 2021)
Vomiting, in particular, is a hallmark of bulimia, as is diarrhea from laxative abuse, making people with a history of this eating disorder especially vulnerable to relapse
doi: 10.1186/s12933-019-0892-3, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 71
