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This is consistent, the team said, with the prevailing hypothesis suggesting that [semaglutides] therapeutic effects arise from overlapping neurobiological mechanisms that modulate both metabolic regulation and reward-related pathways shared between obesity and alcohol use disorder. The team concluded: Findings from this trial provide support for broadening the indication for semaglutide to [include] AUD in patients with a BMI of 30 or greater, which could benefit millions. About 890 million adults globally have a BMI over 30, and in the U.S., 8 million adults are estimated to have obesity and high alcohol consumption

Every Metabolyz patient is supervised by a licensed clinician who reviews your history, authorizes treatment where appropriate, and adjusts your plan over time

Neogi T, Guermazi A, Roemer F, Nevitt MC, Scholz J, Arendt-Nielsen L, et al

Cancers 16 , 2377 (2024)

Avoid heavy, fatty, or spicy meals for dinner

Side effects are generally mild and covered in the AOD-9604 side effects article